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San Francisco 49ers at Arizona Cardinals

Game data updated 3 min ago · this page re-reads every 10 min while open

Week 18, 2026 · State Farm Stadium · Sunday, Jan 10, 12:00 AM ET · closed

San Francisco 49ers
6–1 · Elo 1619 · Brock Purdy
Elo: SF 78%
Arizona Cardinals
3–5 · Elo 1439 · Gardner Minshew II (−87 Elo) · Home

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What the forecasters say

ForecasterFavorsARISFNote
EloSF 78%22%78%ARI 1439 vs SF 1619, implied spread ARI +8.7
The blendSF 78%22%78%

The System's number and our picks of the week are for signed-in players. Sign in to see them.

The spot: Everything else

Moderate favorites where the models roughly agree. No edge found either way in the replays. The blend is as good as anything.

No market line yet.

Details

Injury report

ESPN's report, refreshed every three hours. Out and doubtful players are treated as unavailable; questionable players usually play. Only the quarterback feeds Elo directly; the rest is in the market's number.

TeamPlayerPosStatusInjury
SFBrandon AiyukWROutPersonal · Aiyuk is close to hiring new representation and is expected to file for reinstatement to the NFL in the near future, according to NFL reporter Jordan Schultz.
SFChristian McCaffreyRBQuestionableHamstring · McCaffrey is dealing with a mild hamstring strain rather than a quadriceps injury, and the 49ers believe he'll be ready following the team's Week 8 bye, David Lombardi of SF Standard reports.
SFDeebo Samuel Sr.WRQuestionableHamstring · Samuel (hamstring) has a chance to return following the 49ers' Week 8 bye, Matt Maiocco of NBC Sports Bay Area reports.
SFGarret WallowLBQuestionableHamstring · questionable
SFLuke GiffordLBQuestionableGroin · questionable
SFMarques SigleSQuestionableAnkle · questionable
SFMike EvansWRQuestionableAchilles · Evans (Achilles) is expected to return after San Francisco's Week 8 bye, David Lombardi of SF Standard reports.
SFNick BosaDEQuestionableKnee · San Francisco head coach Kyle Shanahan said Monday that Bosa (knee) "has a chance" to return to action Nov. 8 versus the Raiders following a Week 8 bye, David Lombardi of SFStandard.com reports.
SFUpton StoutCBQuestionableShoulder - AC Joint · Stout (shoulder) was only active as an emergency depth option during Sunday's loss to the Falcons, David Lombardi of SFStandard.com reported Monday.
ARIJon Gaines IIGOutAnkle · out
ARIKendrick BourneWROutLower Leg · Bourne suffered a fractured right tibia during Sunday's overtime win at Dallas that won't require surgery but will sideline him for three months, ending his 2026 season, Adam Schefter of ESPN reports.
ARIWalter Nolen IIIDTOutAnkle · out
ARIBam KnightRBQuestionableConcussion · Head coach Mike LaFleur revealed Monday that Knight is in the concussion protocol following Sunday's overtime win in Dallas, Josh Weinfuss of ESPN.com reports.
ARIJayden WilliamsOTQuestionableKnee · Williams (knee) has been ruled out for the rest of Sunday's game against the Cowboys, Darren Urban of the Cardinals' official site reports.
ARIJeremiyah LoveRBQuestionableAnkle · Head coach Mike LaFleur said Monday that Love suffered a "new" ankle injury during Sunday's overtime win at Dallas, and that he'll have an update on the running back later this week, Josh Weinfuss of ESPN.com reports.
ARIMichael WilsonWRQuestionableRibs · Wilson said after Sunday's 33-30 win at Dallas that he suffered two broken ribs during the contest, Josh Weinfuss of ESPN.com reports.

On the Wire

Lions at Dolphins: 87°F heat at kickoff Sunday 1 PM ET. Cardinals at Seahawks: 15 mph wind at kickoff Sunday 4 PM ET. In wind of 15+ mph, favorites have won 62% against a 65% forecast over 27 seasons; The System shrinks toward 50. In heat above 75°F favorites underperform slightly; The System shrinks a tenth. Read more →

Jaguars at Ravens: Ravens on 4 days' rest; Jaguars on 4 days' rest. Browns at Saints: Saints off a bye. Giants at Eagles: Giants off a bye. Broncos at Panthers: Panthers off a bye. Texans at Chargers: Texans off a bye. Raiders at 49ers: 49ers off a bye. Packers at Patriots: Packers off a bye. Read more →

Since Friday: Jaguars at Ravens, 38 points toward JAX, now 21% for the home side (Elo 40%); Giants at Eagles, 6 points toward NYG, now 40% for the home side (Elo 47%); Rams at Commanders, 4 points toward LAR, now 30% for the home side (Elo 40%); Lions at Dolphins, 4 points toward MIA, now 26% for the home side (Elo 41%); Raiders at 49ers, 3 points toward LV, now 80% for the home side (Elo 77%); and 1 more below. Read more →

Line movement

No market has priced this game yet. Kalshi and Polymarket usually list games about a week out; sportsbooks earlier.